EchoMRI™ Quantitative Magnetic Resonance Body Composition Analyzers for animals and humans take direct measurements of total body fat, lean mass, free water, and total body water. The measurement principle depends on the density of hydrogen nuclei and the physical state of the tissue.
More rapid, accurate, and precise than other methods, EchoMRI™ technology allows for fast measurements (about 1min for mice and rats and less than 3min for humans) in vivo without anesthesia or sedation. Unlike DEXA, Echo measurements are radiation-free, do not require the subject to remain still, and in a peer-reviewed study yielded 24 times DEXA's precision facilitating convenient, low-stress repeated tracking of small changes in body composition. Moreover, Echo instruments measure fat and lean mass as an independent characteristics, unlike DEXA, which measures the fat to lean ratio and is, therefore, prone to error propagation from lean to fat. The systems are much less expensive than conventional MRI, are completely silent, and do not require advanced training to use.
In short, EchoMRI™ is the only technology on the market today which allows body composition analyses to be conducted in such a short period of time, with such a high level of precision, without the need for anesthesia or sedation of the test subject(s), with the subjects entirely comfortable during and in preparation for the measurement, and with no radiation to be considered as a health issue.
特色:
功能:
The EchoMRI™ proprietary method for tissue characterization provides measurements of whole body composition parameters: fat mass, lean tissue mass, free water, and total body water. The data obtained by EchoMRI™ are highly correlated to those obtained by DEXA, but the measurement procedure is faster and does not require anesthesia. In fact, the measurement duration is about 1 minute for mice and rats and about 3 minutes for humans.
1. 可測的體內成分參數:
2. 可測的對象: 活體清醒動物、死亡動物及組織檢體,包括了: Mice,Rat,大動 物,人,斑馬魚,昆蟲,種子,Tissue,Biopsy .
3. 可應用於肥胖症、糖尿病及新陳代謝疾病等研究
EchoMRI™: features and benefits
The key benefit of the EchoMRI™ systems to those involved in research is the precision and accuracy they offer when compared to those of DEXA. When Nuclear Magnetic Resonance (NMR) is applied toward the analysis of body composition during clinical trials, it has an effect on the accuracy, precision, sensitivity, and specificity of results. It is far superior in its ability to offer precise and accurate results for researchers and clinicians.
機款 Models:
產品名稱 |
EchoMRI-100 |
EchoMRI 3-in-1 |
EchoMRI-700 EchoMRI-900 |
EchoMRI Custom |
EchoMRI-AH |
動物型態 |
Mice |
Mice |
Rats |
Various animals |
Humans |
體重範圍 |
<100 g |
活體動物: 15~100 g 組織樣品: 0.2~15 g 組織切片: 10~500 mg |
EchoMRI-700:100~700 g EchoMRI-900:250~900 g |
可測不同的體重範圍及大小 |
60 kg~250kg |
測量時間 |
< 1 min |
< 1 min |
< 1 min |
<1 min |
<10 min |
檢測項目 (g) |
全身脂肪量total body fat 瘦肉量lean muscle mass 全身含水量total body water 體液含量body fluids |
· 活體動物: 瘦肉量lean muscle mass 全身脂肪量total body fat 全身水量total body water 游離體液free body fluids · 組織樣品: 脂肪fat 非脂肪組織lean tissue 游離液體free fluids · 組織切片: 脂肪fat 非脂肪組織lean tissue 游離液體free fluids |
全身脂肪量total body fat 瘦肉量lean muscle mass 全身含水量total body water 體液含量body fluids |
全身脂肪量total body fat 瘦肉量lean muscle mass 全身含水量total body water 體液含量body fluids |
全身脂肪量total body fat 瘦肉量lean muscle mass 全身含水量total body water 體液含量body fluids |
Q. Does the machine generate heat? If so, how much?
A. The device has five core components: a magnet, sensor assembly, analog electronics, digital electronics, and an LCD monitor. The Rat/Mouse magnets are permanent, not electromagnets, and, therefore, generate no heat. The Adult Human magnet is an electromagnet but generates a relatively small amount of heat, equal to a computer workstation. The operation of the antenna assembly generates a negligible amount of heat. The analog electronics box generates a small amount of heat so that the box does not even need a fan. The most heat generated by the instrument comes from the digital electronics, which has a standard computer-type fan that exhausts about as much heat as a typical personal computer or a typical light bulb. In a normal laboratory environment, no special air conditioning or environmental settings are required.
Q. What are the safety issues with EchoMRI™? What is the magnetic field in the vicinity of the EchoMRI™ system? Is any special shielding required?
A. No special shielding is required. For the Rat/ Mouse/ 3-in-1 systems, the magnetic field induction is less than 5 X 10-4T, excluding volume that is less than 9" (0.2m) from the gantry. The Adult Human system has a 5-gauss field that extends approximately 65"/ 26cm from the magnet covers.
Q. What are the features and benefits of EchoMRI™ systems?
A. The key benefit of the EchoMRI™ systems to those involved in research is the precision and accuracy they offer when compared to those of DEXA. When Nuclear Magnetic Resonance is applied toward the analysis of body composition during clinical trials, it has an effect on the accuracy, precision, sensitivity, and specificity of results. It is far superior in its ability to offer precise and accurate results for researchers and clinicians.