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细胞机械牵拉仪器Mechanical Cell Strain Instrument-STREX ST-195 Microscope Mountable & ST-140 Bench Top

 

STREX - Mechanical Cell Strain Instruments

How will your cells respond to strain, tension, and deformation?
  • Simulate natural cellular mechanical strain
  • Consistent strain over days
  • Uniform strain across sample
  • Cell culture or tissue samples
  • Customized or pre-designed strain parameters
  • Real-time monitoring
  • Streamlined for easy use

Simulate physiological cellular mechanical strain in cell culture using STREX Mechanical Cell Strain Instruments. Classic cell culture conditions are static compared to in vivo where living cells are mechanically active. While mechanical strain governs natural processes such as bone, muscle, lung, skin, and stem cell maturation, stress is often the cause of most pathologies such as loss of tissue architecture and cellular morphology. Using STREX, cells are seeded onto a silicone strain chamber for stretch or compression that simulates in vivo mechanical strain experienced by cells.


Resources
• Application Notes • References • Microscopy • Video demonstration •

Instruments


Bench Top

  ・Time trials
  ・Fluorescent and light
   microscopy
  ・Long duration studies
  ・Unidirectional stretch
  ・Strain 1-5 chambers at one
    time


Control Unit

Microscope Mountable
  ・Real-time observation of cultures
  ・Fluorescent and light microscopy
  ・Short duration studies
  ・Uni or bidirectional stretch or compression

 

Mechanical Cell Strain Instrument
STREX ST-195
Microscope Mountable



ST-195 mounted on a inverted microscope and attached to the STREX Controller



ST-195
The versatile ST-195 allows real-time observations of cell cultures under precise, controlled strain conditions. This instrument has 64 different strain parameters in addition to a microscope mountable CO2 incubator. The thin silicon strain chamber used by the ST-195 is compatible with inverted microscopes and fluorescence microscopy. ST-195 can be used with Nikon, Olympus, Leica, and Zeiss microscopes.


Features ST-195
Purpose
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes)
Strain Chambers
Strain Uniaxial stretch
# chambers strained at 1 time 1
Volume/chamber 4cm2
Inside dimension (WxDxH) 20 mm x 20 mm x 10 mm
Strain Parametersa
Degree of strain 2, 4, 6, 8, 10, 12, 15, & 20%
Single strain (sec) 3, 5, 10, 60
Cycles/min 1, 10, 20, 30
# strain programs 64
Microscope mountable models
Microscope fits Nikon, Olympus, Zeiss, Leica
Self-contained CO2 Incubator Yes

aThese are an example of parameters that some researchers use.

Mechanical Cell Strain Instrument
STREX ST-190-XY
Microscope Mountable



ST-190-XY with 4 cm2 XY chamber

Features ST-190-XY
Purpose
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes)
Strain Chambers
Strain Uni or biaxial stretch & compression
# chambers strained at 1 time 1
Volume/chamber 4cm2
Inside dimension (WxDxH) 20 mm x 20 mm x 10 mma
Strain Parametersb
Degree of strain 2, 4, 6, 8, 10, 12, 15, & 20%
Single strain (sec) 5, 10
Cycles/min 1, 10, 20, 30
# strain programs 64
Microscope mountable models
Microscope fits Nikon, Olympus, Zeiss, Leica

aArea of the strain chamber that is subjected to the full amount of both the X and Y stretch/compression.
bThese are an example of parameters that some researchers use.


Mechanical Cell Strain Instrument
STREX ST-150 Microscope Mountable



Control and regulate cell stretching or compression of a single cell culture on a microscope stage. Computer controlled so you can precisely regulate the degree and frequency of the strain to produce 64 unique strain parameters. The ST-150 is compatible with Nikon, Olympus, Leica, and Zeiss microscopes.

ST-150 with 4 cm2 strain chamber
Features ST-150
Purpose
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes)
Strain Chambers
Strain Uniaxial stretch
# chambers strained at 1 time 1
Volume/chamber 4cm2
Inside dimension (WxDxH) 20 mm x 20 mm x 10 mm
Strain Parametersa
Degree of strain 2, 4, 6, 8, 10, 12, 15, 20%
Single strain (sec) 3, 5, 10, 60
Cycles/min 1, 10, 20, 30
# strain programs 64
Microscope mountable models
Microscope fits Nikon, Olympus, Zeiss, Leica

Mechanical Cell Strain Instrument
STREX ST-140-04 and ST-140-10



Automated instrument designed to hold 5 or 6 strain chambers with precise uniaxial mechanical strain. The robust and easy to use design ensures that cells grow over long periods of time with regular cyclic stretching or compression. This unit allows you to control the frequency and degree of the strain to produce 64 unique strain settings. The instrument fits in a standard cell culture incubator.

ST-140-04 with 4 cm2 chamber
Features ST-140-10 ST-140-04
Purpose
• Gene or protein expression
• Cytoskeletal reaarrangements
• Time Trials
• Long term studies (houres - days)
Strain Chambers
Strain Uniaxial stretch Uniaxial stretch
# chambers strained at 1 time 6 5
Volume/chamber 4cm2 10cm2
Inside dimension (WxDxH) 20 mm x 20 mm x 10 mm 32 mm x 32 mm x 10 mm
Strain Parametersa
Degree of strain 2, 4, 6, 8, 10, 12, 15, 20% 2, 4, 6, 8, 10, 12, 15, 20%
Cycles/min 1, 6, 10, 20, 30, 40, 50, 60 1, 6, 10, 20, 30, 40, 50, 60
# strain programs 64 64
ST-190-XY is an automated instrument with a thin silicon strain chamber to observe cells in real-time using light or fluorescence microscopy. Biaxial strain that is experienced by endothelial, muscle, and fibroblast cells can be simulated by mechanical stretching or compression along the X and Y axis of our strain chamber. Strain can be applied simultaneously or independently along the X and Y axis. This versatile unit can perform 168 different strain parameters and is compatible with Nikon, Olympus, Leica, and Zeiss microscopes.


XY strain chamber

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