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Mechanical Cell Strain Instrument-STREX ST-195
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| [ 作者：佚名 | 来源：本站原创 | 点击数：3322 | 更新时间：2008-12-01 ] |
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STREX - Mechanical Cell Strain Instruments
How will your cells respond to strain, tension, and deformation?
- Simulate natural cellular mechanical strain
- Consistent strain over days
- Uniform strain across sample
- Cell culture or tissue samples
- Customized or pre-designed strain parameters
- Real-time monitoring
- Streamlined for easy use
Simulate physiological cellular mechanical strain in cell culture using STREX Mechanical Cell Strain Instruments. Classic cell culture conditions are static compared to in vivo where living cells are mechanically active. While mechanical strain governs natural processes such as bone, muscle, lung, skin, and stem cell maturation, stress is often the cause of most pathologies such as loss of tissue architecture and cellular morphology. Using STREX, cells are seeded onto a silicone strain chamber for stretch or compression that simulates in vivo mechanical strain experienced by cells.
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Resources
• Application Notes • References • Microscopy • Video demonstration •
Instruments
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・Time trials
・Fluorescent and light
microscopy
・Long duration studies
・Unidirectional stretch
・Strain 1-5 chambers at one
time |
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Control Unit
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Microscope Mountable
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・Real-time observation of cultures
・Fluorescent and light microscopy
・Short duration studies
・Uni or bidirectional stretch or compression |
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Mechanical Cell Strain Instrument
STREX ST-195
Microscope Mountable
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ST-195 mounted on a inverted microscope and attached to the STREX Controller
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 ST-195 | |
The versatile ST-195 allows real-time observations of cell cultures under precise, controlled strain conditions. This instrument has 64 different strain parameters in addition to a microscope mountable CO2 incubator. The thin silicon strain chamber used by the ST-195 is compatible with inverted microscopes and fluorescence microscopy. ST-195 can be used with Nikon, Olympus, Leica, and Zeiss microscopes.
| Features |
ST-195 |
| Purpose |
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes) |
| Strain Chambers |
| Strain |
Uniaxial stretch |
| # chambers strained at 1 time |
1 |
| Volume/chamber |
4cm2 |
| Inside dimension (WxDxH) |
20 mm x 20 mm x 10 mm |
| Strain Parametersa |
| Degree of strain |
2, 4, 6, 8, 10, 12, 15, & 20% |
| Single strain (sec) |
3, 5, 10, 60 |
| Cycles/min |
1, 10, 20, 30 |
| # strain programs |
64 |
| Microscope mountable models |
| Microscope |
fits Nikon, Olympus, Zeiss, Leica |
| Self-contained CO2 Incubator |
Yes |
aThese are an example of parameters that some researchers use.
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Mechanical Cell Strain Instrument
STREX ST-190-XY
Microscope Mountable
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ST-190-XY with 4 cm2 XY chamber
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| Features |
ST-190-XY |
| Purpose |
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes) |
| Strain Chambers |
| Strain |
Uni or biaxial stretch & compression |
| # chambers strained at 1 time |
1 |
| Volume/chamber |
4cm2 |
| Inside dimension (WxDxH) |
20 mm x 20 mm x 10 mma |
| Strain Parametersb |
| Degree of strain |
2, 4, 6, 8, 10, 12, 15, & 20% |
| Single strain (sec) |
5, 10 |
| Cycles/min |
1, 10, 20, 30 |
| # strain programs |
64 |
| Microscope mountable models |
| Microscope |
fits Nikon, Olympus, Zeiss, Leica |
aArea of the strain chamber that is subjected to the full amount of both the X and Y stretch/compression.
bThese are an example of parameters that some researchers use.
Mechanical Cell Strain Instrument
STREX ST-150 Microscope Mountable
Control and regulate cell stretching or compression of a single cell culture on a microscope stage. Computer controlled so you can precisely regulate the degree and frequency of the strain to produce 64 unique strain parameters. The ST-150 is compatible with Nikon, Olympus, Leica, and Zeiss microscopes.
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ST-150 with 4 cm2 strain chamber | |
| Features |
ST-150 |
| Purpose |
• Calcium mobilization
• Ionic channels
• Real-time observation
• Short-term studies (15-20 minutes) |
| Strain Chambers |
| Strain |
Uniaxial stretch |
| # chambers strained at 1 time |
1 |
| Volume/chamber |
4cm2 |
| Inside dimension (WxDxH) |
20 mm x 20 mm x 10 mm |
| Strain Parametersa |
| Degree of strain |
2, 4, 6, 8, 10, 12, 15, 20% |
| Single strain (sec) |
3, 5, 10, 60 |
| Cycles/min |
1, 10, 20, 30 |
| # strain programs |
64 |
| Microscope mountable models |
| Microscope |
fits Nikon, Olympus, Zeiss, Leica | |
Mechanical Cell Strain Instrument
STREX ST-140-04 and ST-140-10
Automated instrument designed to hold 5 or 6 strain chambers with precise uniaxial mechanical strain. The robust and easy to use design ensures that cells grow over long periods of time with regular cyclic stretching or compression. This unit allows you to control the frequency and degree of the strain to produce 64 unique strain settings. The instrument fits in a standard cell culture incubator.
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ST-140-04 with 4 cm2 chamber | |
| Features |
ST-140-10 |
ST-140-04 |
| Purpose |
• Gene or protein expression
• Cytoskeletal reaarrangements
• Time Trials
• Long term studies (houres - days) |
| Strain Chambers |
| Strain |
Uniaxial stretch |
Uniaxial stretch |
| # chambers strained at 1 time |
6 |
5 |
| Volume/chamber |
4cm2 |
10cm2 |
| Inside dimension (WxDxH) |
20 mm x 20 mm x 10 mm |
32 mm x 32 mm x 10 mm |
| Strain Parametersa |
| Degree of strain |
2, 4, 6, 8, 10, 12, 15, 20% |
2, 4, 6, 8, 10, 12, 15, 20% |
| Cycles/min |
1, 6, 10, 20, 30, 40, 50, 60 |
1, 6, 10, 20, 30, 40, 50, 60 |
| # strain programs |
64 |
64 | | | |
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ST-190-XY is an automated instrument with a thin silicon strain chamber to observe cells in real-time using light or fluorescence microscopy. Biaxial strain that is experienced by endothelial, muscle, and fibroblast cells can be simulated by mechanical stretching or compression along the X and Y axis of our strain chamber. Strain can be applied simultaneously or independently along the X and Y axis. This versatile unit can perform 168 different strain parameters and is compatible with Nikon, Olympus, Leica, and Zeiss microscopes. |
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XY strain chamber | |
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