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Pressure-Volume Loop from Scisense
[ 作者:佚名 | 来源:本站原创 | 点击数:2592 | 更新时间:2007-07-16  ]

心血管研究的创新----带压力及流量传感器的动物心导管-Scisense 导管

 

Scisense 导管 是包括应用创新传感器, 压力及流量测量设备(具有专利的超微型半导体测量仪被设计为变换装置) 安置在导管的前端,测量在导管前端的压力和血流量的变化。在对体内不同部位压力和流量信号波形进行准确研究分析时, Scisense管将为您提供最准确的高频率存贮信号, 并记录在计算机数据采集系统中。 Scisense导管己在世界各国广泛地应用于心脏病学研究. Scisense导管压力传感器有极其优越的耐热性和稳定性,并以其卓越的敏感性和准确性著称。 这些压力传感器提供了最好的高信号/低噪音比。 上千mmHg 的压力也不会损坏传感器。 Scisense导管不仅具有许多优势于常规流体充盈导管接外置换装置系统,并能充分适应于任何心血管研究中不同的应用   
 
最好的性价比(是同类进口产品价格的1/2) 及其技术优势 
具体的优点在于:
  • reduced invasiveness;  
  • improved measurement accuracy; 
  • more comprehensive assessment of cardiac function;  
  • greater product reliability compared to competing products       

1.更高的频率特性: Scisense导管提供的频率变化范围是010 千赫兹(Kilohertz) 常规流体充盈导管接外置换装置系统提供的频率变化范围仅有0 20 赫兹, 低谐振频率(25 35 赫兹)      

2.没有人为移动导管所造成的误差;                                                                                                            

3. 准确地定位测量:  测量压力和流量是通过传感器准确地定位, 直接测量所研究部位的压力和血流量,所以Scisense导管不受外在因素的影响。                                                                                                                 

4. Scisense 导管所提供的生理压力和流量变化是确切表示在身体的研究部位, 而不是测量系统的物理特性上。  

5. 易用: Scisense导管及显示器应用时仅有简单的三阶段过程: 调零; 显示器信号放大调整; 传感装置平衡。

 

Pressure-Volume Loop Analysis Summary:
 
Beat by beat pressure-volume parameters include:   
 
Stroke Volume (SV); Contractility (Ejection Fraction, SV/EDV,  dp/dt Max);
Preload (EDV or EDP);  Afterload (aortic and ventricular pressure);
Compliance (dV/dP); Ventricular Stiffness (inverse of compliance);
Elastance(dP/dV); ESPVR End-systolic pressure-volume relationship; 
EDPVR End-diastolic pressure-volume relationship; PRSW Preload-recruitable stroke work; DPdtmax vs Ved dPdt max against end-diastolic volume relationship; Emax Maximal elastance,

Ultra-Miniature Pressure-Volume Catheter

The Scisense Pressure-Volume system brings an advanced solution to the problem of characterizing the cardiac phenotype of transgenics. Our integrated catheter for simultaneously measuring LV pressure and volume is the smallest such catheter in the world and creates the least possible disruption in small hearts.

Only 1.2 French in size, our P-V catheter is the ultimate in the assessment of hemodynamic parameters and cardiac function, allowing continuous measurement of LV pressure and volume. In addition, our sensors are small enough to slip through aortic bands or the lumens of other devices, and no de-bubbling or flushing is required.

The P-V catheter includes our high fidelity pressure sensor (.39 mm diameter) and four electrode rings (.37 mm diameter, .25 mm width). The similar sizes of these components allow for a smooth catheter tip without any bulges that can otherwise make insertion difficult.

For <100g subjects, the inner electrode segment length is 4.5 mm (center to center). For larger subjects (100-500g), the inner segment length is 9.0 mm. For both types of catheter the outside electrode rings are spaced 0.5 mm from the inner rings.

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