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VCU动物颅脑损伤仪-颅脑创伤模型制作
[ 作者:佚名 | 来源:本站原创 | 点击数:4236 | 更新时间:2009-06-11  ]
  细胞颅脑损伤仪(CIC),电子颅脑损伤仪(eCCI)及液压颅脑损伤仪(FPI)

VCU动物颅脑损伤仪

VCU动物颅脑损伤仪可以分为细脑损伤仪(CIC)脑损伤仪(eCCI)液压脑损伤仪(FPI),這三品己广泛应用于世界范围内的颅脑创伤研究中心,是目前唯一的脑创伤模型制作的金标准。

 

脑损伤仪(eCCI);           脑损伤仪(CIC),    液压脑损伤仪(FPI)

electric Cortical Contusion ImpactorCell Injury Controller IIFluid Percussion Injury

液压脑损伤仪(FPI)

液压脑损伤仪(FPI)是由VCU 大学所制作計的,针对经创伤机制研究,成全球研究神经创伤广泛使用的器,基本的件是採取最先power coating process铝制部分的件都已经电度以避免氧化且可以久使用

The FPI is constructed with a sturdy aluminum frame and the basic structure is finished with a state-of-the-art powder coating process. The balance of the aluminum components are anodized to prevent oxidation and guarantee longevity.

FPI assembly includes the base pendulum mast, graduated protractor, ball bearing-enhanced impact hammer assembly, acrylic fluid cylinder and bracketry, transducer housing, transfer tube and a digital transducer. The device is completed with a self-calibrating Trauma Inducer Pressure Inducer Amplifier.

脑损伤仪(eCCI)是由VCU 大学所制作设计的,針对颅脑创伤机制研究。

脑损伤仪(eCCI)件有: sturdy aluminum frame, animal platform, controller and impactor headAnimal plateform可以和各的立定位搭配。是藉由controller來控制撞的速度,撞击头件部份有含感器,可以決定速率、撞深度及撞位置

The eCCI is constructed with a sturdy aluminum frame to maximize rigidity, thereby ensuring impact accuracy. The support base, animal platform and impactor head are anodized to prevent oxidation and assure equipment longevity.   

Product assembly includes the base and support frame, and adjustable animal positioner with an aluminum animal platform to be used in conjunction with a variety of stereotactic mounts. This model utilizes the enhanced linier motor driven impactor and controller. The enhanced impact head also houses a photo-optic sensor to determine velocity, impact depth and dwell, and is extremely reproducible.

脑损伤仪(CIC)

 损伤控制(CI採取子式控制,適合morphologic、病理理及培养组织损伤后的机制、形态学、病理性。损伤控制针对Flexcell Int’l corp具有利的tissue culture system损伤控制平均把压缩气体送到每个culture wells,以造成培养组织牵张性的损伤损伤重程度是依据气体在密culture well出的量,损伤控制(CIC)是可以搭配Flex ® 29.45cm2 culturing trays I (针对VCU早期的损伤控制)BioFlex® 57.75cm2 culturing trays。因根据所採用的种类损伤的程度、培況,受损后胞或许会上述因素死掉或要修,所以VCU损伤控制(CIC)很適合用在下列:胞受、修,死亡,药物介入的反

The Cell Injury Controller II is an electronically controlled pneumatic device that allows the study of morphologic, physiologic and biochemical responses of tissue-cultured cells to trauma.

Depending on the cell type, the degree of injury and the culture conditions, the injured cells may die or repair. Therefore, the system can be employed to study the responses to trauma, including cell injury, repair, death or pharmacologic intervention.

The CIC II has been designed for use with a patented, commercially available tissue culture system from Flexcell International Corp. in Hillsborough, N.C. Tissue cultures are grown in culturing wells with stretchable Silastic® membrane bottoms. The CIC II regulates the flow of compressed gas to rapidly pressurize individual culture wells, causing a radial stretch injury to the culture. Injury severity is determined by controlling the flow of gas in and out of the sealed culture well and the peak pressure is captured to provide an accurate indicator of radial stretch.

The CIC II accepts both the Flex I® 29.45cm2 culturing trays, which were used with the earlier CIC Model 94A, and the BioFlex® 57.75cm2 culturing trays.

 

 

 

 

 

 

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