神经科学: 脑切片机、行為分析、疼痛研究

清醒大鼠脑电图实时监测仪 NEU-12-CON+ Continuous EEG on Awake Rat

清醒大鼠脑电图实时监测仪 清醒大鼠脑电图实时监测仪.pdf

The system was designed for continuous monitoring of EEG signals of conscious rat and mouse. The set-up can be expanded from one to eight channels. Swivels keep the continuous electrical contact between the amplifiers and sensors. The EEG signals are measured by Experimetria Ltd.’s high quality CRS-EEG amplifier and recorded, stored and analyzed by our S.P.E.L Advanced Neurosys EEG data acquisition system. The computer system can be adjusted so that it switches on inly in a case when a significant change occurs in the EEG signal.

The system can be equipped with stimulatiors. For the different stimulation methods Experimetria provides the appropriate electronics. Various stimulation possibilities are:

· light

· voice

· electrical


For electrical stimulation our first class ground free programmable stimulator is available.

Optional infrared camera with picture processing computer system for continuous monitoring is available.

The advantage of this system lays in its flexibility. Parallel with the EEG monitoring, as the primary function, the system can be expanded to a complete behavior monitoring system.  Several different investigation set-ups can be constructed with the variation of the available accessories:

· NEU-08-CON Conducta examination box and 8 channel software

· NEU-08-CON-01 Digital video recorder 8 channel software module

· NEU-08-CON-02 Digital video recorder camera and computer card with console

· NEU-08-CON-03 Stimulation grid for electric stimulation

· NEU-08-CON-04 “Mouse option” for rat examination box that enabling the rat box to use it mouse too

· AMP-04-EXT Extra- and intracellular signal amplifier with head stage (2 channel)

· SOFT-05-02-NEUR S.P.E.L. Advanced Neurosys EEG software for data acquisition and analysis

· Swivel

· Stative

· Crown (EEG cranium sensor) (10 pcs/ package)

· FAR-01-01 Faraday cage


The modern and newly developed plexi glass cage has been designed on such a way that the animal may be housed in it for weeks. Additional advantage of the design is that the lower tray and grating are independently and easily accessible for cleaning.

References:

Year

Title

Journal

Authors


2004

Comparison of the effect of subacute organophosphate exposure
on the cortical and peripheral evoked activity in rats

Pesticide Biochemistry and Physiology 79 (2004) 94–100

András Papp, László Pecze, Tünde Vezér


2009

Subacute intratracheal exposure of rats to manganese nanoparticles_ behavoiral electrophysiological and general toxicological effects

Inhalation Toxicology,2009;21(S1):83-91

Leila Sárközi, Endre Horváth, Zoltán Kónya, Imre Kiricsi, Brigitta Szalay, Tünde Vezér, András Papp


2009


Functional neurotoxicity of Mn-containing nanoparticles in rats


Ecotoxicol.Environ. Saf. (2010),doi:10.1016/j.ecoenv.2010.09.002

Gábor Oszlanczia,
Tünde Vezér, Leila Sarkozia, Endre Horvath,
Zoltán Konyab,
András Papp


2010

Metal deposition and functional neurotoxicity in rats after 3-6 weeks nasal exposure by two physicochemical forms of manganese


Environmental Toxicology and Pharmacology 30 (2010) 121–126

Gábor Oszlánczia, Tünde Vezéra, Leila Sárközia, Edina Horváth, Andrea Szabó, Endre Horváth, Zoltán Kónyab, András Papp


2012

General and Electrophysiological Toxic Effects of Manganese in Rats following Subacute Administration in Dissolved and Nanoparticle Form



Scientific World Journal. 2012; 2012: 520632.

Edina Horváth, Zsuzsanna Máté, Szabolcs Takács, Péter Pusztai, András Sápi, Zoltán Kónya,
László Nagymajtényi,
András Papp


2014


In vitro intrinsic optical imaging can be used for source determination in cortical slices

EUROPEAN JOURNAL OF NEUROSCIENCE
Volume 39, Issue 1, January 2014,
Pages: 72–82


Sándor Borbély, Csaba Körössy, Zoltán Somogyvári, Ildikó Világi


2014

In vitro intrinsic optical imaging can be used for source determination in cortical slices

European Journal of Neuroscience,
Vol.39, pp.72–82, 2014

Sándor Borb, Csaba Korossy, Zsolt Somogyvári, Ildikó Világi

SEN-14-EEG Implantable EEG sensor (fixed on skull)

SEN-14 is part of the continuous EEG measurement on awake rat system (NEU-12). Placed on rats' skull and connected to the pre-amplifier through a commutator unit.