鼠活动及温度监测系统-UID Mouse Matrix
Home cage activity and temperature monitoring system for rodents
For comprehensive understanding of mouse phenotypes, continuous monitoring of their activity and behavior in the absence of external stimuli is crucial. While video-based systems offer remote monitoring, they are expensive, labor-intensive, and prone to experimenter bias as they rely on research staff fully dedicated to video interpretation. Additionally, conventional temperature recording methods, which involve intrusive devices and frequent handling, are stressful for the animals and challenging in group-housed or nocturnal settings.
The UID Mouse Matrix offers an innovative solution designed to overcome the challenges researchers face when monitoring temperature and activity in socially-housed mice. This RFID-enabled system allows continuous and remote tracking of digital biomarkers, such as locomotor activity and temperature, for one or multiple mice within their home-cage environment. The system can monitor group-housed mice 24/7 in a completely undisturbed setting, even during the dark phase. By eliminating experimenter bias and providing real-time data collection, it facilitates frequent and accurate measurements of progressive behavioral and physiological changes in the same animal over time. We partnered with the leading manufacturers of rodent housing systems (Allentown and Innovive) to enable remote monitoring capabilities with high-density IVC rack systems.
Simply insert the miniature microchip in the animals, and place them back in their cage. The UID Temperature-sensing microchip provides mouse tracking capabilities and reliable temperature measurements with unmatched accuracy to ±0.1oC.
Place the UID Mouse Matrix reader under the cage for continuous (24/7) and undisturbed tracking of the animals’ temperature and activity. The Matrix reader actively polls its antennae (plate zones) to scan the cage for the presence of any microchip within range. Once detected, the microchip activates and sends relevant data (Animal ID, Temperature, Location, Time/Date) to the data collection software. Zone transitioning is done in rapid succession with timing adjusted by the user’s specifications.
The UID Matrix Software collects and records the data from the Matrix system(s) as often as every 100-250 milliseconds. The program automatically captures physiological and behavioral biomarkers in real-time (24/7), and these data can be accessed remotely or stored for further analysis.