Contract Preclinical Research--临床前基础研究
美国健康医疗仪器国际公司AHMSIC于新世纪之初创建于美国纽约，借新世纪之春风快速成长。 AHMSIC由董事会、总经理室、 财务部、 科研部 、 临床部、 人力资源部、 成都办事处、技术支持中心、网络中心构成。 公司拥有数十名优秀的生物医药领域美国专家，组成学术顾问团队，在美国纽约为您提供全方位科研实验、新药研发外包服务: 实验总体设计与实施、数据分析整理、科研论文修改。 公司的专业化实验技术服务涵盖了细胞生物学、分子生物学、动物实验三大研究领域，尤其在心血管新药研发, 动物行为、学习、记忆, 药物滥用, 泌尿和胃肠新药研发等方面拥有丰富的经验。
美国健康医疗仪器国际公司是一家具有中国情结的专门从事临床前基础研究的美国本土高科技企业, 志力于推动国际合作，
我们为您提供如下服务:
心血管、神经、泌尿和胃肠新药研发, 动物行为、学习、记忆, 药物滥用,
新药研发外包服务(美国纽约)
Services Offered:
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Learning and Memory:
- Cued and Contextual Conditioning
- Passive/ Active Avoidance
- T-maze
- Morris Water Maze
- Radial Maze
- Olfactory Learning & Memory
- Straight Alley
- Social Memory
- Barnes Maze
- Conditioned Fear
- Holeboard
- Place Recognition
- Fear-Potentiated Startle
- Biel Maze
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Depression:
- Tail Suspension
- Forced Swim
- Differential Reinforcement of Low Rate of Responding (DRL)
- Holeboard
- Intracranial Self Stimulation
- Social Interaction
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Fear/Anxiety:
- Light Dark Exploration
- Elevated Plus-Maze
- Ultrasonic Vocalization
- Active/Passive Avoidance
- Conditioned Fear
- Fear Potentiated Startle
- Open Field
- Vogel Conflict
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Drug Abuse
- Place Conditioning
- Intracranial Self-Stimulation
- Sensitization/Withdrawal
- Intravenous Self-Administration
- Drug Discrimination
- Alcohol Consumption
- Progressive Ratio Schedules
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Attentional Deficits:
- Prepulse Inhibition of Startle
- Latent Inhibition
- Passive/Active Avoidance
- Serial-Reaction Time Task
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Activity/Motor Deficits
- Open/Field
- Circadian Wheel Running
- Rota-Rod
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Urology/Urodynamics/Urogenital
- Animal models of bladder dysfunction
- Outflow obstruction
- Chemical cystitis
- Spinal cord injury
- Inflammatory cystitis
- Urodynamic testing, cystometry
- Contractility of isolated muscle segments
- Penile erection model
- Calcium imaging
- Membrane potential
- Single cell electrophysiology, patch clamp recording of ion channel activity
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Gastrointestinal Function
- Colonic motility
- Models of irritable bowel syndrome
- Inflammatory bowel
- Constipation
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General Physiological/Pharmacological Testing
- Smooth muscle function
- In vitro and in vivo studies
- Development of study protocols
- Evaluation of varying doses and routes of administration
- Collection and analysis of blood and tissue samples
- Monitoring of animal health, weight, appearance, etc.
- Monitoring of consumption of food and water
- Short-term or long-term studies
- Delivery of samples to you for analysis in your laboratory
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Resources include:
- 2,600 ft2 Animal Care Facility
- Animal Quarters
- Automatic Cage Washer
- Testing/Procedure Rooms
- Surgery Suite/Necropsy Room
- Behavioral Lab Suite
- Operant and Pavlovian Conditioning Systems
- RotoRod
- Mazes
- Video Tracking
- Open-Field Activity
- Self-Administration
- Conditioned Place Preference
. . . and much more
- 7,500 ft2 Analytical, Biochemical, Physiology, Pharmacology Lab Space.
- GC, HPLC, UV-Vis, IR, Fluorescence, Various In Vitro Test Systems
