LABORAS is a measurement system which is used to recognize automatically behaviours of small rodents (mice and rats). The system is currently the only system in the market which is able to determine a large number of different behaviours without traditional human observation. The following behavioural elements can be distinguished: climbing, drinking, eating, grooming, immobility, locomotion and rearing. In addition the system determines the following tracking parameters: position, speed, maximum speed, traveled distance and position distribution. Recently, LABORAS release 2 was launched with an improved user interface and faster processing capability. Laboras SpecificationsLABORAS is designed for and with the help of laboratory animal researchers, which has resulted in a system that is easy to use and matches your research needs. Below we have summarized the main functions and performance of the Laboras equipment. Laboras is a modular system, so it is possible to configure the system with different combinations of functions and to upgrade the system at a later moment.
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SONOTRACK is an advanced non-invasive measurement system to monitor ultrasonic sounds produced by animals. By using a dedicated microphone and hardware the system is able to pick up ultrasonic vocalizations (USV) of animals generated at frequencies between 15 kHz and 100 kHz. |
LABORAS Publications
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Bison, S.; Carboni, L.; Arban, R.; Bate, S.; Gerrard, P.A.; Razolli, M.; Differential behavioral, physiological, and hormonal sensitivity to LPS challenge in rats International Journal of Interferon, Cytokine and Mediator Research 2009:1, page 1-13 (2009) Full article |
2008
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Woolley, M.L.; Pemberton, D.J.; Bate S.; & Corti, C.; Jones, D.N.C. The mGlu2 but not the mGlu3 receptor mediates the actions of the mGluR2/3 agonist, LY379268, in mouse models predictive of antipsychotic activity Psychopharmacology, (2008) 196:431–440 Full article |
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Wood, N.I.; Goodman, A.O.; Van der Burg, J.M.; Gazeau, V.; Brundin, P.; Björkqvist, M.; Petersén, A.; Tabrizi, S.J.; Barker, R.A.; Morton, A.J.; Increased thirst and drinking in Huntington's disease and the R6/2 mouse Brain Research Bull, 76 (1-2):70-9 (2008) Full article |
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Inglis, J.J.; McNamee, K.E.; Chia, S.; Essex, D.; Feldmann, M.; Williams, R.O.; Hunt,S.P.; Vincent, T. Regulation of pain sensitivity in experimental osteoarthritis by the endogenous peripheral opioid system Arthritis & Rheumatism Vol. 58, Issue 10, Pages 3110 -3119 (Sept. 2008) Details |
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Avsaroglu, H.; Sommer, R.; Hellebrekers, L.J.; Van Zutphen, L.F.M.; Van Lith, H.A.; The effects of buprenorphine on behaviour in the ACI and BN rat inbred strains Laboratory Animals, 42 (2008), Page 171-184 Detail |
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Van der Burg, J.J.M.; Bacos, K.; Wood, N.I.; Lindqvist, A.; Wierup, N.; Woodman, B.; Wamsteeker, J.I.; Smith, R.; Deierborg, T.; Kuhar, M.J.; Bates, G.P.; Mulder, H.; Erlanson-Albertsson, C.; Morton, A.J.; Brundin, P.; Petersén, A.; Björkqvista, M. 'Increased metabolism in the R6/2 mouse model of Huntington's disease' Neurobiology of Disease, 29 (2008), Page 41-51 Full article |
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Franěk, M.; Vaculín, Š.; Rokyta, R. 'Changes of locomotor activity in animal models of neuropathic pain' 12th World Congress on Pain, Glasgow, Scotland (August 2008) Poster |
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Hedenqvist, P. 'Anaesthesia and analgesia for surgery in rabbits and rats, a comparison of the effects of different compounds' Doctorial Thesis, Karolinska Institutet, Stockholm (2008), ISBN: 978-91-7357-578-2 Full report |
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Takahashi, A.; Yap, J.J.; Zitzman Bohager, D.; Faccidomo, S.; Clayton, T.; Cook, J.M.; Miczek, K.A. Glutamatergic and GABAergic modulations of ultrasonic vocalizations during maternal separation distress in mouse pups Psychopharmacology (2009) 204:61–71 Full article |
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Hansen, E.; Agmo, A.; Precopulatory Ultrasonic Vocalizations in Rats: Noise or Communications? Poster University of Tromsoe (2006) Poster |
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Portfors, C.V.; Types and Functions of Ultrasonic Vocalizations in Laboratory Rats and Mice Journal of the American Association for Laboratory Animal Science (2007) Full article |
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Oliveira, A.R.; Barros, H.M.T. |
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Metris b.v. / Dr. Ellen Molewijk 'High Quality Simultaneous Measurements of Rodents Behaviour, Tracking, Physiology, Sleep Stages and Ultrasounds' Touch Briefings, Future Drug Discovery 2006, (report January 2006) Full article |
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Holy, T.E.; Guo, Z. |
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Metris b.v. / Dr. Ellen Molewijk 'High Quality Measurements of Rodents Behaviour, Tracking and Ultrasounds Using LABORAS and SONOTRACK' Touch Briefings, Future Drug Discovery 2005, (report January 2005) Full article |